The BISM Case Essay Example | Topics and Well Written Essays - 500 words

The BISM Case - Essay Example A: The research clearly points out to the needs and attitude of modern day office staff – they want to work in a team environment and at the same time they want a bit of privacy for increased concentration on the job. The essential change in hierarchical to cross-departmental process thinking lies in two important factors namely, a) work execution at lowest possible levels and b) informality in cross-departmental consultations without going through bureaucratic procedures – these indicate productivity at the individual level and teamwork at company-wide, rather than departmental level. These two factors impact the way a modern office and its furniture/equipment are designed. For companies like Knoll, this change in an office environment means a very significant change in the way its products are designed and marketed. Failing to realize such changing demands would mean losing market to better-designed products. A: The five productivity factors revealed in the research work, point to the need for self-contained workstations that offer personalized space, the flexibility of movement and at the same time, a sense of participation in a team atmosphere. Work itself is to be executed with the state-of-the-art computer technology. Furniture and workstation are to be integral to each other. While designing the workstation, care will be taken to understand the space needed for the specific electronic equipment like telephones, computers and peripheral items like printers and stationery items. Equally important will be the free tablespace that is required for off-computer work, using traditional paper and pen/pencil. In other words, the integrity of design with work requirements will be of prime importance. Work requirement may change from time to time and this may involve regrouping of staff to execute a specific project.

Internet regulation vs Free

Internet regulation vs Freedom of Speech Essay MGM v. Grokster case determines the file sharing software. Grokster is a software development company that makes peer-to-peer file sharing software making it possible for all users to share files. However, one possibility with the usage of this software is that some users start sharing copyrighted files. Most commonly copyrighted music mp3 files are shared. In this case court determined that whether making of such software can be regulated. Proponents argue that file sharing is very popular and important technology implemented today in several companies for important business tasks. It is also commonly used by individuals for normal sharing of files for important reason. Only for just one reason it is not possible to shut down the whole business. This is just beginning of the exploration of current use of technology which may expand later. Court determined that whether Grokster should be liable for this file sharing that involves copyrighted material. The pro of this case is that today as we’re bound with each other via world wide networking, it has changed the way of our living. Regulating things going on Internet has recently affected our legislations. With internet networking we can easily connect together and communicate. However, recently several cases have emerged and made it more complex to handle people communicating on the internet. There is another law case that is very hot these days, a Yahoo case. Yahoo has been disgraced in France and now fighting with Chinese government on several issues of free speech. All legal aspects of internet regulation include several security measures and protection from threats. In addition, the way of communication on the Internet has made it much easier for anyone to pass any remarks to any person far away from the location. Speech and communication on the internet has to be regulated in order to protect people from any kind of abuse. According to the Judge decision of freedom of speech that the Yahoo had the right in favor it. The con of this case is that though, we know that all humans have rights. Freedom of speech is one of the rights an individual have by birth, but this right has a limitation as well. The limitation is decided by the exposure of the speech on makes in his social environment. Freedom of speech is a right until this freedom doesn’t hurdle the other’s same right. And if this come to happen the ‘right’ of one rests no more with him. Many firms and legislations are now restricting making use of language and topics on the communication board and email. For example, many big firms like Mircrosoft do not allow specific topics to be discussed on their forums. In China a journalist was imprisoned because of the fact that he forwarded an email that contained an inappropriate language terms. Many U. S. firms are now help resolving issues in China regarding communication. Different law now governs freedom of speech on the Internet. Whatever the case it must now be the matter of great concern to regulate everything that is going on Internet. Similarly, USA and other countries several such cases were detected. Many groups, forums and companies do not allow free talk on politics and religion in order to avoid hot debates involved on these topics. In the present circumstances, especially whereby the social environment has become digital, it’s become very crucial to maintain an equilibrium so that each one can enjoy his right of freedom of speech in the most effective way. The most prominent platform for present digital social environment is ‘internet’ which has not only reduced the distances among the continents, but has also opened the opportunities for individuals to have their say on broader channels. This outgrowth in the outreach of common man’s voice has lead him to be confident on one hand and made others to suffer from the un censored voice. Law gives the right to speech, freedom of thought, freedom of choice, freedom of choosing a religion and changing beliefs. Though we have right for freedom of expression but this does not determine that we can use abusive language, make false statements, and defame others. References Internet Regulation law. Retrieved from http://bubl. ac. uk/LINK/i/internetregulation-law. htm Kirby, Carrie (2005). Chinese Internet vs. free speech Hard choices for U. S. tech giants Retrieved from http://www. sfgate. com/cgi-bin/article. cgi? file=/c/a/2005/09/18/MNGDUEPNLA1. DTLtype=tech Supreme Court Hears Two Cases Critical For Future Of Online Free Speech. Retrieved from http://www. aclu. org/scotus/2004/13918prs20050329. html

The Link Between Drugs And Crime Criminology Essay

The Link Between Drugs And Crime Criminology Essay It is a crime to use, possess, manufacture, or distribute drugs classified as having a potential for abuse (such as cocaine, heroin, marijuana, amphetamines, alcohol and many more). Drugs are also related to crime through the effects they have on the users behavior and by generating violence and other illegal activity in connection with drugs trafficking. This research paper will discuss some main causes and effects of using drugs, also look at the statistical data and theoretical model of drug use. Drug addiction can be found in many forms. Drug addiction causes people to use drugs more and more. It also changes the passageways inside of the brain and causes physical damages to the nerve cells. There are also other factors that can lead to drug addiction. One of the factors is genetic. If parents in any family are addicted to drugs then the possibility for children to be addicted to drugs are more because it passes from one generation to next, also children look at their parents and can adapt their habit of using drugs. This is the reason that addiction problem can be found in certain families than the others. One other factor is personality that makes people to rely on drugs. Sometimes, curiosity makes people to try a drug, or if someone is diagnosed with depression, attention deficit disorder, hyperactivity, stress, anxiety or aggression, this can also lead to drug addiction. Children with low confidence and healthy self-esteem have a possible chance of using drugs to overcom e their problems. (Wicker, 2010). One other factor is peer pressure. Kids especially from high school are the most popular group who are more into drug problem because they think that if they will use drugs that will make them very cool and brave person in the eye of other kids and by taking drugs, they can be accepted as a part of the group. Most of the time, People who have a drug addiction problem try to sell drugs to kids because kids can be easily adaptive to drugs. Nowadays, it is very easy to get an access to drugs. Drugs can be found anywhere. For example, neighborhood, schools, shopping malls, offices, factories, etc. Drugs can also be used as a substitution to pain because it numbs the pain for a limited period of time and can give people a relax feeling physically and emotionally. Life is getting tougher day by day. It includes lots of struggle and too much depression especially past life experiences that are very hard to cope with. Most of the time people think that by taking drugs they can be able to for get all their past life experiences and can have a better sense of emotion coping with life problems. Over all, people who use drugs more often become dependent of drugs by the time. (Wicker, 2010). The effects of drug addiction are huge. It not only changes the persons brain chemistry but also behavior over a period of time. It shows very harmful effects on persons health physically and mentally which can lead to criminal activity. Other effect of drug addiction is on family. People with an addiction problem usually involve in lots of different illegal activities that family members and society might not accept it and those activities create problem for the members of family to be accepted in a respectable society. So, family can either assure safety, provide support for their drug addict member that can help that person to stay away from drugs or they can involve in his activities and be a part of it. Drug addiction problem has a vast effect on the law too. Every day, news channels present different types of stories related to drug addiction crimes. For example, murder, car theft, property theft, burglary, selling illegal drugs, shooting, etc. (Wicker, 2010). The National Library of Medicine estimated 20% of all people in the United States have used prescription medication for non-medical purposes (Wicker, 2010). The misuse of prescription and illegal drugs can change the persons behavior by which a person can be easily dragged toward more criminal activities. The major effect of drug addiction is on American economy. The National Institute on Drug Abuse spent almost $67 billion per year for drug addiction programs which includes the total cost of law enforcement, imprisonment, treatments, and other programs. The impact of drug addiction on crime rate is huge and is increasing day by day. (Wicker, 2010). In 1994, Office of National Drug Control Policy examined that in the United States drug use and criminal activities are somehow correlated to each other, and continuous use of drugs and sale not only destroying the members of society but it is also giving rise to more violent criminal activities. In 2000, a survey was sponsored by the U.S Department of Health and Human Services, National Institute on Drug Abuse (NIDA) was conducted on the 8, 10, and 12 graders of high schools and they reported that 54% of senior graders use drugs once in their lives. (Carpino, 2000). According to Carpino: In examining the State and Federal prison inmates who reported being under the influence of drugs at the time of their offense, the Bureau of Justice Statistics (1997) reports the following. 24.5% of Federal and 29% of State prison inmates reported being under the influence of drugs when committing violent offenses. 10.8% of Federal and 36.6% of State inmates reported being under the drugs while committing property offenses. 25% of Federal and 41.9% of inmates reported being under the influence of drugs when committing drug offenses. 24.4% of Federal and 22.4% of State prison inmates reported being under the influence of drugs when committing weapon offenses. In 2009, there were 13,687,241 total arrests in the United States. In which, drug arrests was 1,663,582, total marijuana arrests, 858,408, total marijuana sale arrests was 99,815, total marijuana possession arrests was 758,593, total violent crime arrests was 581,765 and total property arrests was 1,728,285. (Borden, 2008). There are three theoretical models proposed by Goldstein that helps in determining drug related crime in the United States, and they also describes the relationship between drugs and crime. The first model he proposed was psychopharmacological model which suggests that people usually involve in criminal activity when they are intoxicated by drugs. Drugs has an impact on nervous system by which people lose their self-control, their ability of thinking right or wrong which lead them to commit crimes. Every drug has its impact on nervous system but some drugs have strong impact, and associated with violent types of crime. Those drugs are PCP (phencyclidine), cocaine, methamphetamines, barbiturates, and alcohol. In 1998, 218 homicides were committed in New York, and 14% of all killings were associated with psychopharmacological factor which means drugs were involved in all those crimes. (Casavant Collin, 2001). The second model that Goldstein proposed was economic-compulsive model which proposes that people usually involve in criminal activity in order to get money to buy drugs. People who cannot live without drugs often commit crimes to get money because drugs these days are very expensive and not everyone can afford them. The crimes that are related to economic compulsive model are theft, prostitution, fraud, drug trafficking etc. The third model proposed by Goldstein was systemic model. This model suggests that criminal activity among drug dealers rise from drug market. According to systemic model, the main reason of violence between drug dealers, merchant, or different types of organizations is the power to control over territories, neighborhood, streets, and school. In this model, crime is as organizational management strategy. In 1980s, 74% of homicides in New York were related to systemic model. (Casavant Collin, 2001). In United States, crime rate is increasing day by day. Government is spending millions of dollars to control over drugs and its related crime by increasing police man power, establishing organizations that are teaching the side effects of taking drugs and what type of crime a person can commit. Drug addiction causes and its effects are very obvious. The three theoretical models presented by Goldstein supports that there is a connection between drugs and crime. Statistics from different government organizations also supports the crime rate due to drugs. Not all the crimes are related to drugs but by looking at all these facts conclusion can be made that there is a link between drugs and crime.

Flann OBrien, Dickens and Joyce: Form, Identity and Colonial Influence

Flann O'Brien, Dickens and Joyce: Form, Identity and Colonial Influences All quotations from The Third Policeman are taken from the 1993 Flamingo Modern Classic edition. In this essay I intend to examine Flann O'Brien's The Third Policeman in the context of the time of its writing, 1940, its relation to certain English novelistic traditions and also the broader Irish literary tradition in which it belongs. Seamus Deane refers to Ireland as a "Strange Country" and indeed O'Brien's own narrator recalls the words of his father: " . . . he would mention Parnell with the customers and say that Ireland was a queer country." (7) Such a concurrence indicates to a degree the peculiar nature of the Irish situation with regard to theoretical post-colonial models. There is a temptation to see all Irish work since the revival in terms of decolonization. Cahalan, in The Irish Novel, traces the tendency of Irish writers such as Swift, Edgeworth and Maturin to employ fantastic elements and non-realism in direct opposition to English colonial models and in affirmation of certain Irish traditions. Mercier, in The Irish Comic Tradition, points also to the presence of exaggeration, absurdity and scatological detail in Gaelic heroic cycles and poetry. In Flann O'Brien, Bakhtin, and Menippean Satire, M. Keith Booker begins by saying; "It has now become commonplace to think of Flann O'Brien along with James Joyce and Samuel Beckett as the three great Irish fiction writers...

Fire Rescue Department In Malaysia Engineering Essay

In Malaysia, Fire Rescue Department or popularly known as Bomba is the fire and deliverance services bureau. The fire safety criterions must be implemented by following the ordinances in the Uniform Building By-Law ( UBBL ) 1984, National Fire Protection Association ( NFPA ) Codes and Standards and Fire Services Act 1988.2.1.1 Uniform Building By-Law ( UBBL ) 1984Uniform Building By-Law ( UBBL ) 1984 is a published papers, which is used as a needed safety criterion and besides is emphasized by the authorities. The Standing Committee recommended that life safety of the edifice residents must be considered first and it is to be achieved by giving the minimal demand sing to the assorted facets. The assorted facets refer to issue for the residents, spread of fire within the edifice or from one edifice to another one edifice and agencies of sensing and extinction of fires. In UBBL 1984, 80 per centum emphasized on life safety demand and 20 per centum are staying on the belongings protection of a edifice ( Goh, 2009 ) . Besides, the basic demands of the UBBL are equal fire protection stuffs and building system to do certain the safety of the life and belongings in the edifice during the fire. Furthermore, UBBL 1984 besides stated some fire demands sing the building design in order to minimise and diminish the hazard of fire. Automatic fire sprinkler system is mentioned in Uniform Building By-Law 1984 at Part VIII ( Fire Alarm, Fire Detection, Fire Extinguishment and Fire Fighting Access ) .2.1.2 National Fire Protection Association ( NFPA )National Fire Protection Association is an international non-profit organisation which is authorized on fire, electrical and edifice safety. The NFPA was established in 1896 and it serves as the universe ‘s prima advocator in fire bar and is an important beginning for information on fire safety ( Tharmarajan, 2007 ) . Besides that, NFPA develops, publishes, and disseminates about 300 consensus codifications and criterions which intended to minimise the effects of fire and other hazard. Actually for every edifice, procedure, service, design, and installing in society today is already affected by NFPA paperss ( National Fire Protection Association, 2009 ) . Automatic fire sprinkler is mentioned in NFPA 13 ( Standard for the Installation of Sprinkler Systems ) , NFPA 25 ( Standard for the Inspection, Testing, Maintenance of Water-Based Fire Protection System )2.1.3 Fire Services Act 1988The Fire Services Act 1988 is implemented to do necessary proviso for the effectual and efficient operation of the fire Services Department. In add-on, this act is besides for the protection of individual and belongings from fire hazards and other intents connected therewith. This Act most likely explains the responsibilities of the Fire service Department, which consists of implementing fire bar, fire safety review and fire jeopardy suspension, probe and prosecution ( Tharmarajan, 2007 ) .2.2 Types of fire sprinkler systemsFire sprinkler systems are the most of import and successful of the fire contending systems. There are five chief types of fire sprinkler system which are wet pipe, dry pipe, pre-action, re-cycling and surrogate moistures and dry pipe. The three extra types of fire sprinkler system which are tail-end surrogate, tail-end dry pipe and flood. These three systems may be combined with wet pipe and/or surrogate moisture and dry pipe sprinkler system to organize extensions. The type of sprinkler systems to be selected for the edifice will be depended on type of edifice and type of stuffs to be protected ( Hassan, 1996 ) . For illustration, a storage installation that shops extremely flammable liquids will necessitate a different sprinkler system from a shopping Centre.2.2.1 Wet pipe systemWet pipe systems are the most common fire sprinkler system that have been utilizing in the edifice. This sprinkler system is suited used in het edifices where temperatures remain above 0 and there is no hazard of the H2O in the sprinkler system stop deading ( Hassan, 1996 ) . Water is invariably maintained within the distribution piping. When a fire produced the heat, it will do the nearest sprinkler caputs to open at their operating t emperature. Water will instantly dispatch onto the fire, at the same clip the flow of H2O activates a hydraulicly operated dismay bell outside the edifice and agreements can besides be made to alarm the local Fire Brigade ( Hassan, 1996 ) . Figure 2.1 shows a typical moisture sprinkler system where the H2O supply is taken straight from the H2O chief. Figure 2.2 shows how the pipe connected the dismay valve to an dismay tam-tam and turbine. The entire figure of sprinklers that connected to an installing will be different for light jeopardy, ordinary jeopardy and high jeopardy and, depending on the fortunes. Besides that, the figure of sprinklers system fitted to each installing will change over the scope of 500 to 1000 ( Hassan, 1996 ) . When fire sprinkler systems installed in a high rise edifice, the difference in tallness between the lowest and the highest sprinkler in an installing must non be greater than 45 metres ( Hassan, 1996 ) . Distribution pipes are to be connected independently to the chief rise pipe at the floor being served and no subdivision shall widen to more than one floor, mean that each subdivision being served by a separate chief rise pipe. Figure 2.1 Figure 2.22.2.1.1 Advantages of moisture pipe sprinkler systemSimplicity and dependability systemWet pipe sprinkler systems have the fewest figure of constituents and necessitate less installing clip comparison to other systems. Due to the system ‘s simpleness, the system care may non be performed as the coveted frequence. The dependability of moisture pipe sprinkler system is of import since sprinklers may be used to standby for many old ages before they are needed ( API Group, 2003 ) .Fiscal salvagingThe installing and care disbursal for wet pipe sprinkler system are comparative low ( API Group, 2003 ) . It is because moisture pipe sprinkler systems require least sum of installing clip and besides less service clip is required.Ease of alterationThe plants to modify the moisture pipe sprinkler system include closing down the H2O supply, run outing pipes and doing changes. After so, the undermentioned work is to coerce prove the system and reconstruct it. Additional work for sensing and particular control equipment is evitable which may salvage the clip and cost ( API Group, 2003 ) .Shorter clip to mend after fireWet pipe sprinkler systems require the least sum of attempt and clip to reconstruct after a fire ( API Group, 2003 ) . In most cases, fire sprinkler is reinstated by replacing the amalgamate sprinklers and turning the H2O supply back on. For other types of sprinkler systems, it may necessitate extra attempt to reset control equipment.2.2.1.2 Disadvantages of moisture pipe sprinkler systemThe disadvantages of moisture pipe sprinkler system are that it can non be installed in an country where distribution pipes are exposed to stop deading temperatures. It is because the H2O inside the distribution pipe will go solid if exposed to stop deading temperatures.2.2.2 Dry pipe systemThis system may merely be used in the conditions that it is impossible to utilize a moisture pipe system, or jump moistures and dry type system. Dry pipe sprinkler systems are installed in countries where distribution pipes are exposed to stop deading temperatures. For illustration, dry pipe sprinkler systems will be installed at unwarmed edifices and parking garages. The system between dry pipe system and wet pipe system are different. The difference is that, wet pipe sprinkler systems contain H2O but dry pipe sprinkler systems contain tight air. The tight air is supplied by an electric air compressor, N bottles, or other beginning. In add-on, the air force per unit area inside the pipes that is about one-third to one-half times greater than the maximal H2O force per unit area. Dry pipe sprinkler systems have a valve applauder and dismay port. The map of dry pipe valve applauder is to divide between air force per unit area and H2O force per unit area at the valve interface. When a fire starts, fire release the heat causes a sprinkler caput to open and the tight air would be released. Once this happened, H2O will come in the pipe and fluxing through unfastened sprinkler onto the fire. Due to this system is apt to endure frost harm, it is of import that the pipe work should be self-draining and sprinkler caputs must be fitted above the scope pipes. The figure of sprinkler fitted to each installing shall be within the scope 125 to 500, and depends on whether or non an gas pedal has been fitted to the system ( Hassan, 1996 ) . Figure 2.3 shows how sprinkler caputs fitted above the scope pipe. Figure 2.3 ( Beginnings from Hassan, 1996 )2.2.2.1 Advantages of dry pipe sprinkler systemSuitable for stop deading temperaturesDry pipe sprinkler systems are suited to be installed in countries where distribution pipes are exposed to stop deading temperatures. For illustration, dry pipe installings include unwarmed edifices and parking garages.Suitable for H2O sensitive countriesThe advantage of dry pipe sprinkler systems is that it is suited to be used to protect aggregations and other H2O sensitive countries while the moisture pipe system does non. While a physical harm on the moisture pipe sprinkler systems will do the pipes leaking, dry pipe sprinkler system will non. It will take 1 minute to let go of the air inside the pipes before H2O flowing.2.2.2.2 Disadvantages of dry pipe sprinkler systemIncreased complexnessHarmonizing to API Group, dry pipe sprinkler systems require extra control equipment and air force per unit area supply constituents which will increase complexness o f the systems. If proper care is non followed for this sprinkler system, the system would be less dependable.Higher installing and care costThe installing cost for dry pipe sprinkler system will be higher since the complexness degree is higher and installing clip is longer comparison to wet pipe system. Besides that, the care cost will besides be higher due to labor accomplishment is required to keep this complex sprinkler systems.Lower design flexiblenessThere are rigorous demands sing the upper limit permitted size of single dry pipe systems ( API Group, 2003 ) . These restrictions may impact the ability of an proprietor to do system add-ons.Increased fire response clipThe entire clip taken from sprinkler caput opens until H2O is discharged onto the fire is up to 60 seconds ( API Group, 2003 ) . The fire snuff outing actions will be delay for 60 seconds and caused the fire harm to the edifice addition.Increased corrosion potencyDry pipe sprinkler systems must be wholly drained and dried. If there is H2O staying inside the pipe, it will do corrosion and premature failure. This sort of job will non go on on moisture pipe system because the H2O is invariably maintained in piping.2.2.3 Pre-action systemPre-action sprinkler systems are installed in H2O sensitive environments such as computing machine suites, library and paper records office. When in an existent fire status, these systems will run to salvage the edifice and its constituents from fire harm. It will give earliest warning if detected of burning in the protected countries and which will originate from the action of a fume sensor. This will gives adequate clip for the eruption to be dealt with satisfactorily by utilizing portable asphyxiators. The pre-action system is similar to a dry pipe system and flood system. The difference between pre-action system and dry pipe system is that the air force per unit area may or may non be used for pre-action system. The difference between pre-action system and flood system is that the valve is electronically held closed and standard â€Å" closed † are used for pre-action system. Two separate events must be presented to originate sprinkler discharge onto the fire. First, the sensing system identifies a underdeveloped fire and so automatically sprinkler system would open the pre-action valve. When the pre-action valve is opened, it allows H2O to flux into system shrieking. Second, each of the sprinkler caputs will verify whether there is fire so merely permit H2O flow onto the fire. This system must be self-draining. For pre-action sprinkler system installing, the maximal Numberss of sprinklers that may be fitted to an installing for light jeopardy is about 500, ordinary jeopardy and high jeopardy is about 1000 ( Hassan, 1996 ) .2.2.3.1 Advantages of pre-action sprinkler systemThe double action required H2O releaseThe double action here means that the pre-action valve must run and sprinkler caput must blend so merely H2O release ( API Group, 2003 ) . This characteristic provides dual degree of protection against accidental discharge. With this ground, pre-action sprinkler systems are often installed in H2O sensitive countries such as book libraries, computing machine centres and etc.2.2.3.2 Disadvantages of pre-action sprinkler systemHigher installing and care costPre-action sprinkler systems are more complex with several extra constituents, such as fire sensing system. Thus the installing and care cost will go higher due to the add-ons system required.Alteratio n troublesPre-action sprinkler systems have specific size restrictions which may impact hereafter system alterations ( API Group, 2003 ) . Besides that, system alterations must integrate alterations to the fire sensing and control system to guarantee proper operation.Potential decreased dependabilityThe higher degree of complexness with pre-action sprinkler systems the higher possibility that something may non work when needed. Regular care is needed to guarantee dependability.2.2.4 Alternate moisture and dry pipe systemThis system is used for those developments in which the H2O in the pipes may stop dead when alteration in the clime and where the encompassing temperature does non transcend 70. For illustration, the system is operated ‘dry ‘ in winter and ‘wet ‘ in the summer. The system inside the pipes will be alterations by following the clime, when it is dry pipe system so the pipes contain tight air, and when it is alterations to wet pipe system so the pipes are filled with H2O. In some instances, this system may necessitate a duplicate of the automatic dismay valves, which may be connected in analogue. The benefit of the automatic dismay valves is to installations an easy conversion at the bend of the season. Besides that, the system must be self-draining and the figure of sprinkler fitted to each installing shall be within the scope 125 to 500 ( Hassan, 1996 ) .2.2.5 Recycling systemThe usage of this system is by and large restricted to state of affairs where it is necessary: To restrict H2O harm after a inferno ; To forestall accidental H2O harm caused by any accident mechanical intervention with the pipe work or sprinklers ; and To be able to transport out work on the installing while guaranting that the system remains in a province of preparedness at all times. When pre-action valve bend to open mean than the operation of any heat sensor activates the dismay driven tam-tam and primes the pipe work ready for the at hand gap of one or more sprinklers. If the fire was put out by portable asphyxiators instantly, the heat sensors automatically reset to the normal monitoring place. This has the consequence of originating a hydraulic force per unit area equalisation procedure which may typically take 5 proceedingss to finish. After this has occurred, the pre-action valve will be from opened and turn to closed. If the fire begins to rekindle, the heat sensors will be reactivated and do the pre-action valve once more be opened. After so H2O will be directed discharge to the beginning of the fire. Others installings use electrical clocking units and the usage of electrically meshing circuitry is installed to guarantee that the system will non run entirely because of falling air force per unit area in the pipe work. With this system, any inadvertent harm to either the pipe work, or the sprinkler caputs will non do the chief valve to open. The disadvantage is when secret agents working on such an installing must take attention that they isolate that portion of the system on which they are working from the potentially active chief system. The system must be self-draining and the figure of sprinklers fitted to such an installing must non transcend 1000 ( Hassan, 1996 ) .2.2.6 Deluge systemDeluge sprinkler systems are installed in high jeopardy operations, such as power bring forthing station, chemical storage, weaponries workss, and the countries which store points such as flammable liquids. These sprinkler systems will work together with independent fire sensing systems and disch arge H2O instantly to the protected country during a fire. The flood sprinkler system is similar to a pre-action system. The difference between flood sprinkler system and pre-action system is that the flood sprinkler caputs are unfastened and the pipe is non pressurized with air. Deluge systems are connected to a H2O supply through a flood valve that is opened when fume or heat sensing system is activated. The sensing system is installed in the same country as the sprinklers. When the sensing system is activated, H2O will dispatch through all of the sprinkler caputs onto the fire. Water is non equal to command or extinguishment fire in countries where flammable liquids are manufactured or stored. Water is require to blend with the froth dressed ore and do the dressed ore to spread out when released through the sprinkler caput, it may striping the fire beginning of O required to back up burning of flammable stuffs ( Hassan, 1996 ) .2.2.7 Tail-end surrogate pipe and tail-end dry pipe systemsThese systems may be regarded as an ‘add-on ‘ system to a standard sprinkler installing and they are intended to cover with relatively little countries. In a het edifices will served by a conventional moisture pipe system, it is possible that a little portion of the edifice is either unwarmed or is overheated temperatures. In order to cover with this, it is allowable to fall in a tail-end surrogate system onto the chief moisture pipe system. The figure of sprinklers on any tail-end extension must non transcend 100. If it is more than two tail-end extensions are services by one valve set, the entire figure of sprinklers in the tail-end extension must non transcend 250 ( Hassan, 1996 ) .2.3 Benefit of fire sprinkler systemAutomatic fire sprinkler systems have been used to protect industrial and commercial belongingss for more than 100 old ages. Nowadays, fire sprinklers are non merely installed in commercial and industrial edifices but besides installed in residential edifices, office edifices, schools and hotels. Fire sprinkler systems are become common and popular that is because it is provide many benefits to us.2.3.1 Reduce human deathsIt is hard to gauge how much safer fire sprinklers could supply in the event of fire. Based on grounds from research lab surveies and limited field experience in the United States, the surveies prove that fire sprinklers could salvage an extra 7.7 lives per million houses per twelvemonth . In add-on, the grounds besides proves that fire sprinklers could cut down the hazard of firefighter decease and hurt during put out a fire. It is estimated if all the edifices were installed with fire sprinklers, approximately 0.1 fireman lives could be saved per million houses per twelvemonth. Thus, the survey concludes that fire sprinkler could salvage an extra 7.8 lives per million houses per twelvemonth ( Rousseau, 1989 ) .2.3.2 Reduce hurtsBased on the United Stated research, the survey proves that if installing of fire sprinkler in edifices could forestall about 87 people hurts per million houses each twelvemonth. The sum of firefighting hurts could besides be reduced through increased installing of sprinklers by every bit many as 30 firefighting hurts per million houses per twelvemonth. Based on American Studies, the cost to remedial per hurt to a civilian or fireman is $ 30,000 ( Rousseau, 1989 ) . These costs are included to pay medical measures and allowance for hurting and agony.2.3.3 Reduce Insurance PremiumsResidential fire sprinkler systems are going more prevailing with each go throughing twelvemonth. If the edifice installed with fire sprinkler systems, it will do the extra 1 to 2 % addition in the concluding cost of the house ( Snyder, 2008 ) . Besides that, municipalities must account for the addition in residential system and guarantee that they are being maintained in conformity with current National Fire Protection Association criterions. After installed fire sprinkler systems, they will really salvage money because they can cut down place insurance rates by 5 to 15 per centum ( Snyder, 2008 ) . These values are expected to be increase in the hereafter. In the event that there is a fire, they will besides salvage money in possible amendss.2.3.4 Increase value of the edificeA edifice constructed with fire sprinkler system has more value than a edifice without a fire sprinkler system. It is because a edifice with a fire sprinkler system provides extra fire safety for the edifice and therefore, the edifice worth more and the proprietor could derive more net income when selling the edifice.2.3.5 Reduce belongings harm costHarmonizing to records for decennaries on belongings harm, the proprietor save about 90 % on belongings harm costs with fire sprinkler systems than those without fire sprinkler systems when a fire is happened. This is clear that a fire sprinkler system will pay for itself many times over. Harmonizing to Daniel Snyder article, the mean cost of amendss in places with fire sprinkler systems was about $ 2,000 and the mean cost of amendss in places without sprinkler systems was about $ 45,000.2.3.6 More clip to get awayFire sprinkler systems provide an extra grade of protection for both life and belongings above fume and other fire sensing systems. Sprinkler systems evidently help people by giving more clip for them to get away when a fire is go oning, so they help to salvage lives. A right designed and installed sprinkler system can observe and command a fire at an early phase of fire development and activate an dismay. So with the right operation of the sprinkler system will quickly cut down the production rate of heat and fume, therefore leting more clip for the residents to get away safety or be rescued.2.3.7 Increase issue entree travel distance capacityAn addition in exit entree travel distances is a major distinguishable advantage for edifices with sprinkler system over edifices without sprinkler system. The issue entree travel distance mean the distance from any occupied part of a edifice to an issue. For illustration, the issue is such as enclosed staircase. Depending on the tenancy of the edifice, anyplace from an extra 50 to 100 pess of issue entree travel distance can be gained when the edifice is installed with fire sprinkler system ( International Building Codes, 2006 ) . Table 2.1 show the maximal travel distance between constructing with sprinkler and without sprinkler for different types of edifices. SEVENTH SCHEDULE MAXIMUM TRAVEL DISTANCES ( By-law 165 ( 4 ) , 166 ( 2 ) , 167 ( 1 ) , 170 ( B ) ) Purpose Group Limit when alternate issues are available ( 2 ) ( 3 ) Dead-end bound ( meter ) Un- sprinklered SprinkleredSmall ResidentialInstitutionalHospitals, Nursing Homes etc, School Open Plan Flexible PlanOther ResidentialHotels Flatss DormitoriesOfficeShopsFactoryGeneral and Special Purpose High Hazard Open constructionTopographic points of AssemblyStorage and GeneralLow an Ordinary jeopardy High Hazard Parking Garages Aircraft Hangars ( Ground Floor ) Aircraft airdocks ( Mezzanine Floor ) NR 9 6 NR NR 10 10 0 15 15 15 0 NR NR NR NR 15 NR NR NR 30 45 30 45 30 30 30 45 30 30 22 NR 45 NR 22.5 30 30 22.5 NR 45 60 45 60 45 45 45 60 45 45 22.5 NR 61 NR 30 45 45 22.5 Table 2.1 ( Beginnings from Uniform Building By-Law 1984 )2.3.8 Increase Egress capacityFor the tenancies edifices which are installed with fire sprinkler systems, except high-hazard and infirmary, the agencies of egress constituents can be increased 50 % for the stairway breadth and 33 % for all other egress constituents such as corridors, doors, inclines ( International Building Codes, 2006 ) . For illustration, a 44 inch of issue stairway concept in a edifice which is without fire sprinkler systems merely can function 146 individuals, but a same 44 inch of issue stairway concept in a edifice which is installed with fire sprinkler system can function 220 individuals. Besides that, 44 inch corridor concept with fire sprinkler system can function 293 individuals, without fire sprinkler system can function 220 individuals.2.3.9 Reduce building costAs antecedently reference, if the new edifice installed with fire sprinkler systems, it will do the extra 1 to 2 % addition in the concluding cost of the house. They are non merely can cut low the insurance premiums but besides cut down in building cost. This is because most edifice codifications provide big building leeway for sprinkler edifices. For illustration, fewer emersions are required and larger floor countries are allowed for the edifice with sprinkler systems installed. This executable design will assist proprietors and re sidents to cut down the building cost and stuff cost. Further more information about the advantages of fire sprinkler system relate to benefits of building cost economy will be explain as below:2.3.9.1 Decrease in shaft enclosuresFor edifice are non greater than 420 pess in tallness, the fire evaluation of perpendicular shaft such as HVAC, electrical, plumbing, trash/linen chutes, except issue enclosures and lift hoist manner enclosures, is permitted to be reduced to one hr where automatic sprinklers are installed within the shaft at the top and at alternate floor degrees ( International Building Codes, 2006 ) . This can be a large cost economy in high-rise edifice building.2.3.9.2 Elimination of the entree anteroom for smokeproof issue stairway enclosuresFor tower block edifice, the issue staircases off the floors located more than 75 pess above the lowest degree of fire section vehicle entree are required to be smokeproof issue enclosures ( IBC 1020.1.7 ) . The entree are to the s tairway in a smokeproof issue enclosure is required to be form an unfastened outside balcony ( IBC subdivision 909.20.3 ) or a ventilated anteroom ( IBC Section 909.20.4 ) , with a breadth of non less than 72 inches ( IBC Section 909.20.1 ) . If the high rise edifice is installed with fire sprinkler systems, under IBC subdivision 909.20.5 is allow to extinguish the unfastened outside balcony and /or the ventilated anteroom demands. This alternate saves valuable infinite on each floor of the edifice and it can be converted into rental or marketable infinite for the edifice proprietor. This can be a large cost economy in high-rise edifice building and besides derive excess net income for edifice proprietor.2.4 Problem of fire sprinkler systemFire sprinkler systems can be used to salvage lives, belongings and others benefit, whether they used in industrial edifices, offices, or place. But automatic fire sprinkler systems besides present some alone proficient jobs. Fortunately, such jobs can be avoided by cognizing the most common grounds for fire sprinkler failure. From the National Fire Sprinkler Association study, the most common grounds for fire sprinkler failure that are error sprinkler activate, overheating, stop deadin g, mechanical harm, corrosion, or leaking.2.4.1 Problem sing elements of fire sprinkler2.4.1.1 CorrosionCorrosion or rust can weaken pipes and sprinkler caputs. The terrible corrosion jobs have been normally attributed to microbiologically influenced corrosion and known as MIC. This can ensue a sudden and unwelcome activation when a sprinkler pipe or caput fails. The National Fire Protection Association states that edifice proprietors are responsible for replacing sprinkler constituents that are corroded or rusted. Corrosion of fire sprinkler piping can take to potentially risky system malfunction, every bit good as dearly-won H2O harm and fix costs. Unfortunately, reviews for MIC and corrosion are frequently overlooked until the jobs become serious, such as damaging leaks occur or the corrosion extend to a big countries of the full fire sprinkler system have to be replaced. This disciplinary care attack is a retro-active scheme. The undertaking of the care squad in this scenario is normally to consequence fixs every bit shortly as possible. Cost associated with disciplinary care include fix, lost production and lost gross revenues. Repair costs are included replacing constituents, labor, and consumables.Solution to corrosion of fire sprinklerA new proactive attack to fire sprinkler care is available utilizing wholly non-invasive, supersonic engineerings that from the BASIC of a prognostic care attack ( Jeffrey, 2005 ) . This attack provides a cost-efficient agencies of observing the presence and supervising patterned advance of corrosion and making a digital record of the system province that can be used to schedule replacing of localised subdivisions of the system before leaks or operation failure occur.2.4.1.2 Mechanical harmFire sprinkler systems depend on the unity of all their parts. If a sprinkler caput is hit or a pipe damaged, the parts can divi de and the system can non be activate when fire is present. A common job with sprinkler caputs is harm from nearby building of forklifts that are raised excessively high, by chance strike harding off sprinkler caputs. Besides that, put ining automatic sprinklers can besides ensue in harm to the system if improper tools or techniques are used ( Russell and Fleming, 2000 ) .Solution to mechanical harmFire sprinkler system must ever be inspected after the plants have been completed by contractor or sprinkler provider. Homeowner must guarantee all elements of the sprinklers in proper mode and without harm.2.4.2 Problem sing installing of fire sprinkler2.4.2.1 FreezingThere are two major sorts of fire sprinkler systems which are wet pipe and dry pipe sprinkler systems. Normally wet pipe sprinkler systems are most common used to put in in the edifices. For this sprinkler system, H2O is invariably maintained within the distribution piping. The advantage to this system is that it responds r apidly to a fire and less expensive than other sprinkler systems. The disadvantage to this system is than the H2O in the system could stop dead if installed to stop deading temperatures. The job that is some rawness builder installs this type of sprinkler system exposed to stop deading temperatures and causes the pipes freezing, the H2O inside can turn to frost and spread out. The enlargement can interrupt pipes and adjustments, doing leaks and loss of H2O force per unit area. The enlargement besides can coerce unfastened sprinkler caputs, doing inadvertent activation when the pipes thaw out ( Russell and Fleming, 2000 ) .Solution to shriek freezingThere are three solutions to work out this sort of job. The first solution to this job is to run all sprinkler shrieking inside interior walls and utilize wall mounted sprinkler caputs ( Schunk, 2008 ) . The ground of replace ceiling mounted sprinkler caputs to palisade mounted sprinkler caputs is that the infinite above the ceiling is capable to stop deading temperatures. Another solution to this job is to blend antifreeze into the H2O ( Schunk, 2008 ) . It will forestall H2O inside the distribution pipe freezing when H2O mix with antifreeze. A job with this solution is that the care requires periodic draining of the system and replenishing with the proper mixture. This care is non merely expensive but besides really mussy and hard to execute in a finished house. The last solution to forestall freeze is to put in the fire sprinkler shrieking beneath the ceiling insularity ( Schunk, 2008 ) . This ceiling insularity must do certain use to whole country, uncomplete ceiling insularity even to a little country will do the pipe freezing. In extra, insularity is merely slows down heat transportation and the pipes will finally stop dead if temperatures alterations to really cold. The best manner to forestall this job happen is that the rawness builder or householder must speak to his contractor or sprinkler gross revenues representative about method to maintain fire sprinkler systems from stop deading temperatures. From illustration, the right method to this job that is chooses the dry pipe sprinkler system in the freeze temperatures.2.4.2.2 OverheatingHeat is used to trip fire sprinklers. Fire sprinklers will automatic activate when the heat is detected and no affair the heat will or will non do the harm to people and belongings. Where fire sprinkler are located excessively close to warmer, fanlights, and other beginnings of heat, the fire sprinkler can by chance travel off and dispatch the H2O out.Solution to overheatingHarmonizing to the regulations of National Fire Protection Associated criterion 13, installings of sprinkler systems require that higher temperature rated sprinkler be used. This means that the solder elements or glass bulbs used as the oper ating mechanisms will be designed and replaced with sprinkler caputs that are rated for higher heat. For illustration, normal glass bulbs will trip at temperatures of 68-74 but for higher rate of glass bulbs will trip at temperatures of 93-149 ( Russell and Fleming, 2000 ) . If the heat is above this scope, a qualified contractor should be hired to do the necessary alterations.2.4.3 Problem sing H2O supply2.4.3.1 Water supplyA typical domestic H2O supply for one and two household homes includes a 5/8 † H2O service and metre and may include a H2O force per unit area regulator and/or a backflow preventer. All of these devices are designed for a typical residential H2O flow rate of 5 to 7 gallons per minute. Unfortunately, they can non present the 26 gpm which required by a residential fire sprinkler system. All of these devices need to be increased in size to 1A? † in order the H2O flow rate go 26 gpm ( Schunk, 2008 ) . The job is, a residential H2O force per unit area regulator and H2O metre that are increased in size to manage the higher fire flows will non decently cut down the H2O force per unit area when operating at the low flow rates that are typical in one and two household homes ( Schunk, 2008 ) .Solution to H2O supplySolution to these jobs is to put in a seconded larger H2O service dedicated to the fire sprinkler system. This solution is non merely expensive ab initio, but will hold ongoing cost because many H2O purveyors ‘ have a minimal monthly rate per metre. The minimal monthly rate mean even there is no ingestion but besides back up to pay certain minimal sum. Besides, the rates typically increase with the size of the H2O metre, so the fire sprinkler metre rates will be more so the rates for the domestic H2O metre. Again, adding a seconded larger H2O service and metre is a concealed cost that is because it is portion of the pipe fitter ‘s occupation, and hence non included in the fire sprinkler contractor ‘s command ( Schunk, 2008 ) .

Lockheed management Essay

We examined the decision to invest in the Tri-Star project by forecasting the cash flow associated with the project for a volume of 210 planes. We also asked what a valid estimate of the NPV of the Tri-Star project at a volume of 210 planes as of 1967 would be. We found this to be -$584 M. This was clearly an unacceptable NPV for capital budgeting on the project. A break-even analysis revealed that the project reached economic break-even with the production of 275 planes at $12.5 M per unit but did not reach value break-even at that level of production. Despite industry analysts predicting 300 units as Lockheed’s break-even sales point, at this level, net present value remained insufficient to cover costs at negative $274 million. If the company had performed a true value break-even analysis, management would have realized that roughly 400 Tri Star aircraft (about 67 per year for six years) costing somewhere between $11.75 million and $12 million per unit would have to be sold in order to break even. The investment decision made by Lockheed to pursue the Tri Star program was not a reasonable one. A true value analysis shows that at the production level of 210 units, the project would result in an economic loss of $584.05 million and a profit loss of $480 million. In addition to miscalculating the break-even level of production, Lockheed management overestimated the growth rate of air travel industry.

hurricanes essays

hurricanes essays The second part of our report will be about hurricanes. A hurricane is an intense tropical low-pressure area with winds that are 120 kilometers per hour or greater. Hurricanes are also called tropical cyclone or typhoon. The most damage a hurricane does is when the storm surges hits. Storm surges are currents. They form when the hurricane piles up water along the shore and then blows it inland. They are much more damaging during high tide. Hurricanes grow larger and more powerful from the vast amounts of energy that go into them by condensing water vapor. Unlike a tornado hurricanes have no fronts. The middle of a hurricane is called the eye. The eye of the storm is usually 15 to 150 kilometers in diameter. However because the air in the eye in sinking there is no rain. There is almost no wind either. The eye is surrounded by intense thunderstorms called the eye wall. When you are in the eye of the hurricane you may think it the storm is over but then the other side of the hurricane hits. You may think the storm is over in the eye because there is no wind or rain and the sky may even be blue. The winds in a hurricane get stronger as they go into the center of the hurricane and they are most violent just outside of the eye. When A hurricane is fully growing it is about 650 kilometers in diameter with winds about 120 miles per hour. Unlike a tornado a hurricane can last for days at a time. They die out because they lose moisture. That is the hurricanes main need. Hurricanes require the upwelling of warm and moist air for them to keep on going. This report helped us learn more about hurricanes and tornadoes that we didnt know before. It told us things that were very interesting and that we would never now unless we did this report. ...

Example University of British Colombia Admission Essay

Example University of British Colombia Admission Essay Free Online Research Papers Example University of British Colombia Admission Essay The mission statement of Johnson North Secondary School has provided me the unique opportunity to gain the qualities necessary to be a successful educator. Being a senior student, I was inspired by many teachers and school staff members to give back to the school and community. I believe my experiences working with students through the JNSS mentorship and leadership programs have contributed to the fulfillment of the JNSS mission statement for reaching young students and giving them the opportunity to become exemplary citizens in and out of the school community Currently, I am an executive member of Johnson North’s Students’ Council and Fine Arts Council as well as the Grad Council Chairperson. As an executive member of all these council I work closely with students and staff to organize numerous school-wide events. I am also the Presidents of JNSS Amnesty International and one of the more recent projects that I carefully organized was the 1st Annual Amnesty International Film Festival. Apart from serving others, I also believe in education and I have had successfully finished four dynamic 1st year University level Advanced Placement courses, Biology, Psychology, Macro and Micro Economics in grade 11 and I am currently enrolled in History of Arts Advance Placement. Moreover, I believe in the value of community service and as a volunteer, I have devoted many hours to the Canadian Aids Society, Canadian Downs Syndrome Foundation, as well as the Canadian Kidney Foundation. Just before the winter break of 2006, I spearheaded the 1st Annual Amnesty International Film Festival at JNSS. The Film Festival is a week long event, where two films related to human rights were featured each day in our school gallery. The executives worked closely with the regional director of Amnesty International of Canada and with the support of the staff from the school and the dedication of club members and volunteers, the events was a tremendous success. Through our work, we were able to give students from all grades an opportunity to learn about human rights and make them understand the values and rights that all people are entitled to. Political and social issues such as those facing Tibetans in China, the aftermath of the chemical explosion in Bhopal, India, conflict diamonds in African nations, and the travesty in North Korea, were some of the topics that were covered at our film festival. What fascinated me was the sense of good-will that radiated amongst the students. In a concerted effort to create awareness in our community, we were able to ensure the tremendous success of the event. I am always striving to help other students create and achieve their goals. My leadership at Johnson north has always been accomplished through taking action and helping others. I have been involved in my school’s Grade 8 Mentoring program where senior students are assigned five juniors and I acted as a positive role model for the elementary students in making the leap to high school. My genuine concern for the world’s problem has inspired me to become a high school science and social studies teacher. My endeavor to assist students has not only helped them to reach their full potential, but also allowed me to continue my life’s ambition to be a positive influence on my society and the University of British Colombia. Research Papers on Example University of British Colombia Admission EssayStandardized TestingHip-Hop is ArtPersonal Experience with Teen PregnancyWhere Wild and West MeetDefinition of Export QuotasBringing Democracy to AfricaInfluences of Socio-Economic Status of Married MalesQuebec and CanadaAnalysis of Ebay Expanding into AsiaRelationship between Media Coverage and Social and

Arnold Palmer Hospital Supply Chain

Arnold Palmer Hospital’s Supply Chain Case Arnold Palmer Hospital is one of the nations leading hospitals for women and children. It is located in Orlando, Florida, and is apart of a national purchasing group. Even though being apart of the purchasing group has some advantages, there are also many disadvantages. These disadvantages forced the hospital to change its supply chain strategy. After leaving this group the hospital along with several other hospitals from the group formed their own smaller, but still powerful group, Healthcare Purchasing Alliance.The company saved its members $7 million in the first year with two main changes. First, it was structured and staffed to assure that the bulk of the savings associated with its contracting efforts went to its eight members. Second, it struck even better deals with vendors by guaranteeing a committed volume and signing not 1- year deals but 3- to 5- year contracts. There are several issues facing the Arnold Palmer Hospital (APH) that led to the revising of the supply chain strategy.The main reason for the revision of the strategy was because of the frequent changing of products every year by the purchasing group, because of lower cost bidders. Another reason for the change in strategy is the fact that the purchasing group drops products that are familiar or preferred to APH, and stocked products that were not famili ar to the physicians at the hospital. The final reason the case stated that the hospital changed its strategy was because the buying group was not able to negotiate contracts with local manufacturers to secure the best pricing.Because APH left the large purchasing group and formed their own group they were able to save their members $7 million, even though they had an internal cost of $400,000 to run HPA the savings and ability to contract for what the member hospitals really want makes the business a good one. The reason that Arnold Palmer Hospital’s strategy differs from a manufacturing firms strategy is because an effective supply chain strategy in manufacturing focuses on development of new product innovations and efficiency through buyer-vendor collaboration, where-as the approach in a service industry has a slightly different emphasis.Because APH is a service industry it focuses more on the people side of the supply chain. Using the people who actually use the product and taking their input when buying the objects. The alternative to the problem with the purchasing group would be to do exactly what APH did, leave the group. Although instead of forming their own group they could have joined another group in the area. With them forming their own group they can set their own rules, and regulations, and if they had joined another group they would have had to conform to the already set rules and regulations. I believe that the best alternative that they could have chosen was forming their own purchasing group. That way they can do what was best for them, their patients and their employees, and the other hospitals in the group. They can come up with their own rules and regulations, who they wanted their supplies from, and who to negotiate contracts with.

How can project managers reduce the risk of project failure describe Essay

How can project managers reduce the risk of project failure describe and relate tools and concepts. Illustrate with examples - Essay Example The risks can comprise problems of parts superiority and material; stoppages in delivery of adequate resources to convene project requirements; budgetary and workers transforms; and, imperfect research or knowledge of the project manager. These risks lead speedily to holdup in release dates and financial plan overages that can be harshly weaken assurance in the development of the project management (Martin et al, 2004). There are lots of risk those are attached to the project development and cause a serious problem for the better management and administration of the project. These risks are also the main reasons for the failure of the most of the projects. At project management viewpoints, project managers have to find out the most recent insights, methods and developments in project management field. This will provide him a better understanding regarding the efficient project management and solutions for emerging risks (Johnson et al, 2005). A lot of projects would be unsuccessful for the reasons of declining behind timetable, cost overruns and so forth. Such type of risks can be decreased, if the project manger has good qualities of project risk finding. If a project manager is able to identify the main stakeholders and makes sure that they evidently make out the project scope and main objects of the project. What we can do to diminish the project failure risk? As I have accessed a solid step project managers are able to acquire to augment the accomplishment of all their projects: is the process of enhancing the skills of their team members (Martin et al, 2004). By means of making sure that the project development and management group is properly capable/ trained previous to start a multifarious project. This is very best way through which project manager can be able to significantly diminish the project cost; augment project effectiveness and risk of project collapse predominantly in high-risk projects. So we can say that a project

Equalization in Canada verses Equalization in Australia Essay

Equalization in Canada verses Equalization in Australia - Essay Example Equalization is one of four major federal transfer programs. The others are the Canada Health Transfer, the Canada Social Transfer, and the Territorial Formula Financing (the main source of revenue for territorial governments). Equalization is the federal government's main device for reducing fiscal inequalities between the 'have and have-not' provinces (Mapleleafweb). The grant to receive equalization funding is calculated by a formula assessing each province's revenue raising ability against a five-province standard. Presently eight Canadian provinces receive equalization: Quebec, Nova Scotia, Newfoundland, British Columbia, Prince Edward Island, Manitoba, New Brunswick, and Saskatchewan. This program is the Canadian government's most important initiative for reducing fiscal discrepancies between provinces (Equalization Program). Equalization payments allow less prosperous provincial governments to offer their residents public services such as hospital fees, electricity, water and other basics that are comparable to those in other provinces and at similar taxation levels. Each province receives unconditional equalization payments. ... For 2005-06 eight provinces are expected to qualify for $10.9 billion in equalization entitlements. The provincial governments may spend the equalization money they receive in any way they desire, unlike conditional transfer payments such as the Canada Health and Social Transfer. The equalization payments guarantee equal levels of health care, education, and welfare in all the provinces. Equalization payments do not involve payment transfers from wealthy provinces to poorer provinces. Instead the federal treasury provides the funds for these payments. In other words, for example, a wealthy citizen from a poorer province like New Brunswick, pays more into equalization than a poorer citizen in wealthy province like Ontario. Since Ontario has a bigger population and wealth, the citizens of Ontario as a whole pay more federal taxes and therefore their total contribution in equalization payments is greater than that of New Brunswick. Equalization payments also aid by encouraging national unity. Quebec, the most populous of the poorer provinces, is the largest single beneficiary of the payments. 70% of the 10 million Canadians of the poorer provinces reside in Quebec when British Columbia and Saskatchewan are removed. The history of Equalization dates back to Confederation and the Constitution Act of 1867. Two basic principles that Canada's founding fathers based the separation of legislative powers: 1) The central government must retain much of its revenue generating power for the purpose of building railroads 2) 'Coordinate federalism' in which provincial governments act independently and autonomously within predefined powers and must be the basis for the division of powers between provinces and the central government. The great

Scientific Method Applied to Forensic Science Paper Essay

Scientific Method Applied to Forensic Science Paper - Essay Example The scientific method is applied to forensic science to help forensic scientists gather needed evidence to come to a conclusion about a criminal event. Though it follows the same basic ideas and techniques as the original tried and true scientific method, forensic science has their own tweaked version of the method, which is as follows: observation and description of a phenomenon, or a group of phenomenon; formulation of a hypothesis, or hypotheses, to explain the phenomenon; use of the hypothesis to predict the existence of other phenomenon, or to predict quantitatively the results of new observations; â€Å"performance of experimental tests of the predictions by several independent experiments (James, 2009)†. These methods aid forensic scientists in the solving and understanding of the events of criminal investigations. The first step in the forensic scientific method is to observe and describe phenomenon or a group of such. The forensic scientist needs to be able to understand what they are seeing when they are viewing the crime scene and the evidence that they inspect. â€Å"If they describe it wrong or relay the information incorrectly, they will botch the experiment, thus botching the investigation and lessening the chances of solving the crime accurately (Braswell, 2007)†. They have to focus on the entire crime scene, taking in every bit of information that they can and making note and taking pictures of the totality of the scene. The recording of what they find allows them to look back at everything later, giving them the chance to find new evidence that they overlooked during the initial inspection. They have to look at the scene as a whole, breaking the scene up into smaller sections to further their collection of evidence and comprehension of the crime scene. With closer inspection, they can begin to understand what did take place, so all

Has equality made America freer Research Paper Example | Topics and Well Written Essays - 1250 words

Has equality made America freer - Research Paper Example Due to this, a number of revolts of the slaves were recorded in the 18th up to the early 19th century. (Fede, p. 27) These revolts were caused by the injustices, discrimination and maltreatment to the slaves and to the black community. Due to these revolts, there were some states in the US that abolished slavery. The first state to abolish slavery was Rhode Island in 1774. This act of abolition intensified the hunger of the slaves and the black community for total eradication of the inequalities (Surname) 2 happening in the land. The abolition was followed by Vermont, Pennsylvania, Massachusetts, New Hampshire, Connecticut, New York and New Jersey which transpired from 1777 to 1804. Although the importation of slaves from other countries was banned, selling of slaves continued within the US. (Osborne, p. 11) In 1831, The Liberator, an anti-slavery newspaper was founded by William Garrison and soon thereafter, the American Anti-Slavery Society was formed. A movement of white anti-slav ery Protestants was based on the principles of the Second Great Awakening. Theodore Weld led the liberation of slaves. Caused by the fact that revolts had been here and there, the Congress got tired of the abolitionists. Slavery and discrimination went on even in States where slavery was not allowed. African Americans took on principal roles in the abolition which dominated most part of the South. Both Frederick Douglass (The North Star) and David Walker took part in the revolt against the white tyranny. The Underground Railroad helped slaves to escape from the South. (Fede, p. 43) This fight over equality by the slaves and the black community went on until the signing of the Emancipation Proclamation in 1863. President Lincoln thought that the proclamation would be seen as a temporary measure to the war. Immediately thereafter, in 1864, the Thirteenth Amendment was passed by the Senate followed by the by the House on January 31, 1865. This states that â€Å"Neither slavery nor inv oluntary servitude, except as a punishment for crime whereof the party shall have been duly convicted, shall exist within the United States, or any place subject to their jurisdiction.† (Sundquist, p. 32) (Surname) 3 This amendment was adopted on December 18 of the same year and completely abolished slavery. The US has indeed gone a long way towards the concept of equality which they fought for a tremendous amount of time. The seemed-to-be never-ending battle over slavery officially ended in the reign of the Former President Lincoln. The Thirteenth Amendment was followed by the Fourteenth Amendment in 1868 which stated that â€Å"All persons born or naturalized in the United States and subject to the jurisdiction thereof, are citizens of the United States and of the State wherein they reside. No State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States; nor shall any State deprive any person of life, liberty, or prop erty, without due process of law; nor deny to any person within its jurisdiction the equal protection of the laws.† (Sottiaux, p. 117) Two years after, the Fifteenth Amendment was adopte

Brand Impact and Popular Culture Essay Example | Topics and Well Written Essays - 1500 words

Brand Impact and Popular Culture - Essay Example This paper illustrates that Matthew McConaughey is an American actor well known for his role in films like Dazed and Confused  (1993), Amistad  (1997), and Failure to Launch (2006). In recent years, McConaughey has featured in small, independent films and has featured in some exigent roles. Toyota Corolla was launched in 1966 primarily as a family car. It was positioned as a progressive and friendly vehicle. The newest version of the Corolla is focused on providing an instantaneous good feeling to the customer. There is a picture of a sleek, attractive Toyota Corolla zooming along the river side on the first slide of the theme board. The photograph of a smiling, friendly brand endorser on the same slide is used to encode the feeling of goodness. The Brand Typology model suggests that brands can be classified into eight categories namely Clean Slates, Weak Brands, Little Tigers, Defenders, Olympic, Classic, Specialist and Fading Stars by analyzing their momentum and familiarity in the marketplace. Olympic brands are illustrious and have a large customer base. These brands are usually the talk of the town and serve as benchmarks for other brands. At present Toyota Corolla is an Olympic brand. The car was launched in 1966 and is now pegged as the ‘World’s Most Popular Car’. The Japanese company has manufactured more than 40 million Toyota Corolla cars since its launch. The model is sold in more than 150 countries and regions around the world. McConaughey too is recognized worldwide. The experienced actor has staged a remarkable mid-career comeback and his popularity has increased tremendously in recent times. Good looks, humility, and award-winning performances have made McConaughey an admirable person.

Scientific Method Applied to Forensic Science Paper Essay

Scientific Method Applied to Forensic Science Paper - Essay Example The scientific method is applied to forensic science to help forensic scientists gather needed evidence to come to a conclusion about a criminal event. Though it follows the same basic ideas and techniques as the original tried and true scientific method, forensic science has their own tweaked version of the method, which is as follows: observation and description of a phenomenon, or a group of phenomenon; formulation of a hypothesis, or hypotheses, to explain the phenomenon; use of the hypothesis to predict the existence of other phenomenon, or to predict quantitatively the results of new observations; â€Å"performance of experimental tests of the predictions by several independent experiments (James, 2009)†. These methods aid forensic scientists in the solving and understanding of the events of criminal investigations. The first step in the forensic scientific method is to observe and describe phenomenon or a group of such. The forensic scientist needs to be able to understand what they are seeing when they are viewing the crime scene and the evidence that they inspect. â€Å"If they describe it wrong or relay the information incorrectly, they will botch the experiment, thus botching the investigation and lessening the chances of solving the crime accurately (Braswell, 2007)†. They have to focus on the entire crime scene, taking in every bit of information that they can and making note and taking pictures of the totality of the scene. The recording of what they find allows them to look back at everything later, giving them the chance to find new evidence that they overlooked during the initial inspection. They have to look at the scene as a whole, breaking the scene up into smaller sections to further their collection of evidence and comprehension of the crime scene. With closer inspection, they can begin to understand what did take place, so all

Brand Impact and Popular Culture Essay Example | Topics and Well Written Essays - 1500 words

Brand Impact and Popular Culture - Essay Example This paper illustrates that Matthew McConaughey is an American actor well known for his role in films like Dazed and Confused  (1993), Amistad  (1997), and Failure to Launch (2006). In recent years, McConaughey has featured in small, independent films and has featured in some exigent roles. Toyota Corolla was launched in 1966 primarily as a family car. It was positioned as a progressive and friendly vehicle. The newest version of the Corolla is focused on providing an instantaneous good feeling to the customer. There is a picture of a sleek, attractive Toyota Corolla zooming along the river side on the first slide of the theme board. The photograph of a smiling, friendly brand endorser on the same slide is used to encode the feeling of goodness. The Brand Typology model suggests that brands can be classified into eight categories namely Clean Slates, Weak Brands, Little Tigers, Defenders, Olympic, Classic, Specialist and Fading Stars by analyzing their momentum and familiarity in the marketplace. Olympic brands are illustrious and have a large customer base. These brands are usually the talk of the town and serve as benchmarks for other brands. At present Toyota Corolla is an Olympic brand. The car was launched in 1966 and is now pegged as the ‘World’s Most Popular Car’. The Japanese company has manufactured more than 40 million Toyota Corolla cars since its launch. The model is sold in more than 150 countries and regions around the world. McConaughey too is recognized worldwide. The experienced actor has staged a remarkable mid-career comeback and his popularity has increased tremendously in recent times. Good looks, humility, and award-winning performances have made McConaughey an admirable person.

Nurture as Predictor of Happiness Essay Example for Free

Nurture as Predictor of Happiness Essay Nature versus Nurture as Predictor of Happiness Introduction            Happiness is one trait that is quite difficult to define and explain in human beings since different people have different things which they feel brings happiness to them which may be the complete opposite in other people (Phoenix, 2007, pp.104). One thing that may raise positive emotions in one individual may raise the opposite negative emotions in another person, hence making it quite difficult to have a clear cut definition of happiness. This tends to raise the question of what exactly always makes one happy and what are the relative importances of nature versus nurture as predictor of happiness in human beings. According to Phoenix (2007), â€Å"The behavior of people and other animals cannot be understood without taking account of the influence of their environments as well as their biology† (Phoenix, 2007, p.104). This means that happiness as part of human beings can be an influence of nature or nurture as the main predictors of the happiness of an individual. People who conducted research and came up with the various cause of happiness or the predictors of happiness must have experienced happiness at one point during their lifetime (Spoors, et al, 2007, pp.5).            This could simply indicate that every human being has the chance and opportunity of experiencing happiness in the life at one point. It is not quite easy to provide a straight forward definition of happiness which can be used in general at any time when there is reference to be made concerni8ng happiness. However, happiness may be said to be simply a form of mood which is affirmative and tends to cover a certain variety of emotions which may range from being delighted or even satisfied and conversely (Spoors, et al, 2007, pp.5). The above definition is totally opposed to the dichotomy, because the dichotomy is divided into two parts, for example, joy and sorrow, which are mutually exclusive and simultaneously create a whole. A proven example is a wedding the bride’s. Mother cries for daughter’s wedding, but simultaneously she has joy in it. This happiness is associated with feelings and emotions that people feel the depending on the situation in which they find themselves. In correlation with this, it can be accomplished of happiness and unhappiness cannot be viewed as opposite or mutually exclusive† (Spoors, et al, 2007, pp.5).            According to the assumptions of this concept, the pursuit of happiness, which you want each person is driven by human activities, and at the same time a source of satisfaction, fulfillment, and sometimes a sense of success. Therefore, the benefits associated with happiness include; better health, well-being, a lot greater activity level, willingness to help, and better relationships with others. People who are considered to be unhappy tend not to have the above mentioned emotions and they rarely display such emotions since they have not been able to experience happiness, or even the activities which causes happiness in human beings (Spoors, et al, 2007, pp.5).            When a question is asked about what makes hu8mna beings happy, most of the people would put main focus on the kind of thoughts they have, the kind of relationships that they have which can include close relationships and those that are not close. Furthermore, the question on what makes one happy will also make one to put focus on the brains since it is the one that generates the thoughts which in turn are closely related to the relationships that people have. The factors which act as the determinants of happiness have nature and to some extent have nurture. A healthy lifestyle and a happy brain this nurture issues, because in order for us to have a sense of wellbeing and happiness, our brains and bodies need a consistent source of food and oxygen† (Spoors at al., 2007, pp.26 9, material).            Therefore, it can be agreed that the main causes of happiness which have been suggested as most common include the relationships, the brain and the thoughts. Spoors (2007) observes that for human beings to have a sense of happiness or even well being, they must be able to live a healthy lifestyle as well as have constant supply of oxygen for the functioning of the body and the brain. Furthermore, â€Å"Many people on high protein, high fat, low carbohydrate diets have reported unusually high feelings of anger, tension and depression†, as observed by Spoors (2007). This means that for one to feel happy or have the sense of well being, they must have sufficient balanced diet and also constant supply of oxygen for a healthy body and a healthy brain.            From research conducted by Davidson, people inherit some genes which make one have a genetic predisposition of happiness to a certain level, although this does not mean that there are people who are born unhappy or gloom while others are born happy (Spoors, et al, pp.26-9). According to Shakespeare (2005 edition), â€Å"There is nothing either good or bad, but thinking makes it so†, meaning that what one thinks greatly contributes to them being happy or not. People tend to focus on negative aspects of life whenever they feel they have low spirits. This in turn affects their happiness and instead leaves them feeling much worse. The natural environment where one lives and the kind of nurture and experiences in life contributes to the way one thinks and influences the thoughts that one has, which in turn have been observed to influence the happiness that an individual will display.            This clearly indicates that the thoughts that people have play a major role in them being happy or unhappy. Ellen and Judy (1976) conducted a research and they found out that when people are able to control small issues that affect their life, they are in better position to enhance their happiness (Spoors et al, 2007, pp.53-7). From research which was conducted by Richard Layard (2005), it was observed that there are seven major factors which influence happiness in human beings but the main factor that was identified was close relationships. This same idea was supported by Robert Lane (2000, p. 6), who identified close relationships with families and friends to be great factor that increased human happiness (Spoors et al, 2007, pp.83-5). The views presented by the various researchers regarding the causes or the predictors of happiness are quite convincing considering the kind of research that they have presented is in-depth. Human beings do things because of how th ey feel and most of the actions are more influenced by nature and nurture, which in turn determines the happiness that human beings display. Therefore, it can be said that nature and nurture are both important determinants or the predictors of the happiness of human beings because they all have direct influence on the thoughts, the brain activities and the kind of relationships which people have during their lifetime. References Phoenix, A. (2007) ‘Identities and diversities’ in Miell, D., Phoenix, A. and Thomas, K. (eds)  Mapping Psychology, p.  104. Spoors, P., Finlay, L. and Dyer, E. (2007)  Starting with Psychology p.  5; 26-9; 53-7; 83-5 Source document

Gene Therapy and Genetic Engineering for Curing Disorders

Gene Therapy and Genetic Engineering for Curing Disorders Introduction Now a days Gene therapy is a well known process of treatment of various genetic and other chronic diseases whereas, most of the drugs and vaccines have been discovered till now for almost all the kinds of diseases but still some of the diseases like cancer and AIDS are incurable. Hence, Gene therapy is seeking all the attention and is much beneficial. As gene therapy is the technique that deals with the treatment or the prevention of various diseases. Besides this, Genetic Engineering is another technique which is quite useful for designing, editing or creating a manual recombinant for the sake of getting a better trait, character or expression in the desired species i.e, recombinant insulin production in bacteria. Instead of growing human insulin in bacteria. Genetic engineering could theoretically be used to introduce the insulin gene into human cells that do not possess a functional copy. (That would still not cure diabetes unless these cells were also capable of appropriately increasing or decreasing their output of insulin according to conditions.) This type of genetic engineering is called gene therapy, the introduction of genetically engineered cells into an individual for therapeutic purposes. Three general requirements for gene therapy, first presented in 1980 should be shown in animal studies that; The new gene can be put into the correct target cells and will remain there long enough to be effective The new gene will be expressed in the cells at an appropriate level The new gene will not harm the cell or, by extension, the animal. These three requisites, summarized as delivery, expression, and safety, will each be examined in turn. These criteria are very similar to those required prior to the use of any new drug, therapeutic procedure, or surgical operation. The requirements simply state that the new treatment should get to the area of disease, correct it, and do more good than harm. Some flexibility is necessary since the criteria might be altered for a critically ill patient for whom no further conventional therapy is available. The exact definitions of what is long enough to be effective, what level is an appropriate level, and how much harm is meant by harm, are questions for ongoing discussion as more is learned about gene therapy. Ultimately, local Institutional Review Boards and the National Institutes of Health (NIH), the latter through its newly created Working Group on Human Gene Therapy, must decide if a given protocol is ready for human application. Once the criteria are satisfied, that is, when the probable benefits for the patient are expected to exceed the possible risks, then attempts to cure h uman genetic disease by treatment with somatic cell gene therapy would be ethical. The goal of biomedical research is, and has always been, to alleviate human suffering. Gene therapy is a proper and logical part of that effort. (Anderson and Fletcher, 2010) Many diseases are genetically determined; for example, Huntington’s disease and cystic fibrosis (CF). Others are influenced by genes, but involve additional factors as well; for example, cancer and diabetes mellitus. Recent scientific developments make it possible for medicine to target such genetically related diseases at the molecular level, and thus offer the prospects of effective new therapies. The genes of somatic cells can be manipulated to modify a disease in an individual. If genes in germ cells are modified, a genetic disease may be prevented in progeny as well. In this essay, we will consider some of the scientific, social, and ethical issues associated with such genetic therapies. (Robert George, 2008) Genetic engineering is any process in which an organism’s genome is intentionally altered. Genetic engineering does not encompass traditional breeding techniques because it requires manipulation of an organism’s genes through cloning or transformation via the addition of foreign DNA. This process has five steps: Isolation of the genes Insertion of those genes into a transfer vector (a virus or a plasmid used as a conduit) Transfer of the vector to the organism to be modified Transformation of that organism’s cells Separation of the genetically modified organism (GMO) from organisms that have not been successfully modified. (Kathy, 2010) Genetic engineering is the direct alteration of individual genotypes. It is also called recombinant DNA technology or gene splicing, terms which are used interchangeably. Human genes can be inserted into human cells for therapeutic purposes. In addition, because all species carry their genetic information in DNA and use the same genetic code, genes can be moved from one species to another. (Pratik, 2007) Despite the everyday progresses of medicine solutions for human health, today cancer is still one of the biggest challenges for humanity. Thanks to the advancements in prevention and in treatment, the survival rate has been improved in the last few years. However, cancer remains one of the main causes of death worldwide with 8.2 million of death occurred in 2012. It is estimated that by 2020, there will be between 15 and 17 million new cases of cancer every year, 60% of which will be in developing countries. In economical developed countries the burden of cancer is a result of population aging and growth as well as an increasing adoption of cancer-associated lifestyle choices including smoking, physical inactivity, and ‘‘westernized’’ diets. Cancer, as definition, is the uncontrolled growth of cells that can occur in any type of tissue and, at the late stage, these cells lose their adhesion capacities and migrate to healthy tissues. Other than surgical treat ment, the different options are all based on a mechanical or pharmacological killing action against cancer cells, possibly avoiding the side effect damages of healthy cells. (Marco et al, 2015) Nanotechnology is one of the best promises to attack cancer cells more specifically, effectively and to reduce undesired side effects. In other terms, nanotechnology can be used to transport drugs to a specific site using specific keys such as antibodies. Moreover, in the context of developing innovative theranostics, nanomaterials could be used for imaging as a diagnostic tool and, at the same time, to stimulate and control the release of drugs in the cancer site. In the recent years numerous nanomaterials have been explored for potential theranostic applications for cancer therapy thanks to their properties. Compared to traditional molecular contrast agents or drugs, nanomaterials can be engineered to improve and integrate multiple functions in a single system also to give the control of drugs release, being of hope for the building of a next generation of anticancer tools i.e, Graphene. (Shanmugam, 2014) Materials and Methods Gene therapy is defined as â€Å"the treatment or prevention of disease by gene transfer† and involves the genetic modification of human cells by introducing one or more new genes. There are two types of gene therapy somatic and germ line: †¢ Somatic cell gene therapy involves the genetic modification of any cells in a patient’s body apart from the reproductive cells (egg and sperm). The intention is to confine changes to the individual being treated and the parts of the body where the illness is experienced (such as the lungs with cystic fibrosis) so the genetic alteration should not be passed on to the patient’s children. Somatic cell gene therapy is the only form that is permitted in this country. †¢ Germ line gene therapy involves genetically modifying a fertilised egg and therefore will affect not only the individual that develops from it, but also their offspring and successive generations. Because no actual therapy of an individual is involved, it is more accurately called germ line gene transfer. Although germ line genetic modification of plants and animals is now commonplace, germ line genetic modification of humans is currently banned in this country. This is in line with an existing world-wide consensus that such techniques should not be allowed because of the serious ethical and health implications of modifying the human germ line. (Mountain, 2000) In vivo is the working on germ line gene therapy within an organism. In vitro is related to the somatic cell gene therapy outside the organism i.e, in Lab. Restriction Enzymes Restriction enzymes are enzymes used to cut DNA at specific sites. There are several hundred restriction enzymes currently known and each cuts DNA at a different nucleotide sequence; these target sites are generally about four to eight nucleotides long. Each of these restriction enzymes is a normal product of a particular bacterial species, and most are named after the bacteria from which they are derived. Each species’ restriction enzyme cuts the DNA from other species, but not its own, because its own DNA does not contain the nucleotide sequence that is the target site for its own enzyme. (Pratik, 2007) Methods of DNA transfer Various methods of DNA or gene transfer are as follows; (Sukharev, 2010) Human Gene Therapy At present, the only human tissue that can be used effectively for gene transfer is bone marrow. No other cells (except, perhaps, skin cells) can be extracted from the body, grown in culture to allow insertion of exogenous genes, and then successfully reimplanted into the patient from whom the tissue was taken. In the future, as more is learned about how to package the DNA and to make it tissuespecific, the intravenous route would be the simplest and most desirable. However, attempting to give a foreign gene by injection directly into the bloodstream is not advisable with our present state of knowledge since the procedure would be enormously inefficient and there would be little control over the DNAs fate. Studies are considerably more advanced with bone. Patients with serious genetic diseases have little other hope at present for alleviation of their medical problems. Arguments that genetic engineering might someday be misused do not justify the needless perpetuation of human suffering that would result from an unnecessary delay in the clinical application of this potentially powerful therapeutic procedure. (Anderson and Fletcher, 2010) Arguments against Human Germ line Gene Therapy The ethical arguments against the use of a human germline gene therapy fall into three categories: Potential clinical risks The broader concern of changing the gene pool, genetic inheritance of the human population Social dangers. Ethical Issues Results In recent years, a variety of techniques have been developed to identify genes associated with specific diseases. Since 1990, when the first protocols for gene therapy were approved, over 100 new research protocols have been initiated for a variety of diseases, In the case of somatic cell therapies, the nature of a particular disease and other factors determine the specific cells targeted for genetic manipulation. Target cells have included lung, liver, white blood, endothelial, and cancer cells. All research to date has involved somatic cells, and the techniques used make improbable the spread of altered genes to germ cells. However, it seems likely that we will ultimately be able to alter the genes of germ cells, so that whatever changes are made are passed on to the subjects’ progeny. In current therapies (all of which are somatic cell), vectors are used to introduce new genetic material into target cells. Vectors are agents to which new genetic material is attached. A lot of betterment and efficiency have been observed by the implementation of the methods of gene therapy in curing disorders. Hence, gene therapy along with the genetic engineering plays an important role in the health care of human as well besides the animals and plants. The point is, it is just taken under a limitation by some of the organizations regarding to some ethical issues otherwise it is the futute treatment of all the diseases. Conclusions Gene therapy not only brings the prospect of treatments for previously untreatable illnesses, it may also enable the prevention of certain diseases through the correction of genetic disorders. However, it is clear from gene therapy under development that, in the short to medium term, most gene therapy will not be used for prevention but for developing more effective ‘genebased’ treatments for cancer and AIDS. Although gene therapy has been heralded as a major breakthrough in medical science, it also carries the potential for abuse and for commercial imperatives, not human need, to drive its progress. The demands of industry in maintaining investor confidence may increase the dangers to patients through secrecy and poor supervision. Placing too much emphasis on genes as the determining factor in health and disease may lead to prolongation of suffering as a result of other underlying causes being neglected. It may also give rise to new insidious practices of genetic discrimination in areas such as employment, insurance and health care. Avoiding the pitfalls whilst reaping the benefits of gene therapy is the challenge for politicians and regulators. Crucially, society must not be overcome by ‘genetic determinism’ or ‘genetic thinking’ and the hype of the biotechnology companies if health care issues are to be addressed effectively. References Sade RM, Khushf G., 2008, Gene therapy: Ethical and social issues, Carolina Med Assoc. 94(9):406-410. Kathy Wilson P., 2010, Biotechnology and genetic engineering, pg.12 Pratik Satya, 2007, Genetic Engineering and genomics, pg.95-122. Mountain A., 2000, Human Gene Therapy: A cure for all ills, Tibtech, 18: 119-128. Anderson and Fletcher, 2010, human Gene Therapy, Scientific and ethical considerations, The Journal of Medicine and Philosophy, 10:275-291. Marco Orecchioni, Roberto Cabizza, Alberto Bianco and Lucia Gemma Delogu, 2015, Graphene as Cancer Theranostic Tool: Progress and Future Challenges, Theranostics, 5(7): 710-723. Shanmugam V, Selvakumar S, Yeh CS., 2014, Near-infrared light-responsive nanomaterials in cancer therapeutics, Chemical Society reviews; 43: 6254-87. Sukharev, SI, Klenchin, VA, Serov, SM, Chernomordik, LV Chizmadzhev, YA., 2010, Electroporation and electrophoretic DNA transfer into cells. The effect of DNA interaction with electropores. Biophys, 63 (5):1320-1327.